| Primary Identifier | MGI:2679449 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 245450 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in positive regulation of synapse assembly. Acts upstream of or within axonogenesis. Predicted to be located in dendrite and plasma membrane. Predicted to be active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Is expressed in several structures, including central nervous system; peripheral nervous system; retina; and trigeminal nerve. Used to study non-syndromic X-linked intellectual developmental disorder 111. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual developmental disorder 111. Orthologous to human SLITRK2 (SLIT and NTRK like family member 2). PHENOTYPE: Mice homozygous for a null allele exhibit hyperactivity, decreased exploration, increased coping response, increased vestibuloocular reflex, and disrupted serotonin metabolism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
