| Primary Identifier | MGI:2177151 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 171486 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within diapedesis; positive regulation of T cell extravasation; and positive regulation of neutrophil extravasation. Located in adherens junction and cell surface. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and skin. Orthologous to human CD99L2 (CD99 molecule like 2). PHENOTYPE: Homozygous KO in endothelial cells hinders neutrophil and T cell extravasation and reduces the delayed-type (type IV) hypersensitivity reaction in inflamed tissue. [provided by MGI curators] |