| Primary Identifier | MGI:1330235 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 14404 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GABA-gated chloride ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and inhibitory synapse assembly. Predicted to act upstream of or within chloride transport. Predicted to be located in plasma membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in GABA-ergic synapse; dendrite membrane; and postsynaptic membrane. Is expressed in several structures, including brain; heart; limb; skeleton; and urinary system. Orthologous to human GABRE (gamma-aminobutyric acid type A receptor subunit epsilon). PHENOTYPE: MIce homozygous for a null allele exhibit impaired fertility and impaired response to repeated sevoflurane inhalation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
