| Primary Identifier | MGI:1346343 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 24102 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including 3'-5'-DNA exonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA catabolic process. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human TREX2 (three prime repair exonuclease 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to DMBA- or DMBA plus TPA-induced skin tumors associated with decreased apoptosis in treated epidermis and keratinocytes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
