| Primary Identifier | MGI:1349215 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 11666 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including adenyl ribonucleotide binding activity; organic anion transmembrane transporter activity; and protein dimerization activity. Involved in several processes, including fatty acid metabolic process; negative regulation of biosynthetic process; and positive regulation of fatty acid metabolic process. Located in peroxisomal membrane. Is expressed in several structures, including central nervous system; cranium; genitourinary system; musculature; and respiratory system. Used to study adrenoleukodystrophy. Human ortholog(s) of this gene implicated in adrenoleukodystrophy. Orthologous to human ABCD1 (ATP binding cassette subfamily D member 1). PHENOTYPE: Mice homozygous/hemizygous for disruptions in this gene develop a late onset of neurodegenerative disease (no neurological symptoms up to 6 months of age), with an accumulation of very long chain fatty acids. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
