| Primary Identifier | MGI:109626 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 66826 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity. Involved in several processes, including cardiolipin metabolic process; mitophagy; and spermatocyte division. Predicted to be located in mitochondrial inner membrane and mitochondrial outer membrane. Predicted to be active in mitochondrial membrane. Is expressed in alimentary system; heart; respiratory system; and urinary system. Used to study Barth syndrome and cardiomyopathy. Human ortholog(s) of this gene implicated in Barth syndrome and dilated cardiomyopathy. Orthologous to human TAFAZZIN (tafazzin, phospholipid-lysophospholipid transacylase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility with small testes, azoospermia and abnormal spermatogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
