| Primary Identifier | MGI:1914641 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 67391 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity. Involved in regulation of platelet activation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human FUNDC2 (FUN14 domain containing 2). PHENOTYPE: Homozygous knockout reduces the half-life (increases apoptosis) of platelets in hypoxic conditions, leading to thrombocytopenia. It also leads to increased resistance to thrombosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
