Primary Identifier | MGI:1913974 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 66724 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; molecular adaptor activity; and zinc ion binding activity. Predicted to be involved in defense response to bacterium; non-canonical NF-kappaB signal transduction; and positive regulation of canonical NF-kappaB signal transduction. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including adrenal gland; gonad; liver; lung; and spleen. Orthologous to human TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3). PHENOTYPE: Male chimeras hemizygous for a gene trapped allele appear normal at E9.5. [provided by MGI curators] |