| Primary Identifier | MGI:2687319 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 331461 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; positive regulation of nervous system development; and synapse organization. Located in cell surface and dendrite. Is expressed in central nervous system; dorsal root ganglion; eye; lung; and trigeminal nerve. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability 21. Orthologous to human IL1RAPL1 (interleukin 1 receptor accessory protein like 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit premature giant inhibitory postsynaptic currents and parallel fiber-mediated recruitment of molecular layer interneurons. Knockout also affects behavior in response to physical and virtual novel objects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
