Primary Identifier | MGI:2444925 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 270624 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methylated histone binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Predicted to be located in chromatin; cytoplasm; and nucleus. Predicted to be active in cytosol and nucleoplasm. Orthologous to human SPIN4 (spindlin family member 4). PHENOTYPE: Mice with truncating mutations in this gene show increased overall body size, overgrowth of multiple organs, and increased longitudinal bone growth with increased cell proliferation in the proliferative zone and an increased number of progenitor chondrocytes in the resting zone of the tibial growth plate. [provided by MGI curators] |