| Primary Identifier | MGI:2679294 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 245522 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Acts upstream of or within noradrenergic neuron development; positive regulation of DNA-binding transcription factor activity; and protein monoubiquitination. Located in neuronal cell body. Is expressed in metencephalon basal plate; nervous system; and neural retina. Human ortholog(s) of this gene implicated in Wieacker-Wolff syndrome. Orthologous to human ZC4H2 (zinc finger C4H2-type containing). PHENOTYPE: Mice homozygous or hemizygous for a knock-out allele exhibit neonatal lethality and ventral spinal cord patterning defects. About 50% of heterozygous females display postnatal growth retardation and fail to survive to adulthood, with some embryos exhibiting similar spinal cord patterning defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
