| Primary Identifier | MGI:1933237 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 83558 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in meiotic gene conversion and reciprocal meiotic recombination. Acts upstream of or within several processes, including male gonad development; meiotic nuclear division; and negative regulation of apoptotic process. Located in central element. Colocalizes with synaptonemal complex. Is expressed in oocyte and testis. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 2. Orthologous to human TEX11 (testis expressed 11). PHENOTYPE: Mice homozygous for a knockout allele exhibit abnormal male meiosis. Mice homozygous for a conditional knockout exhibit male infertility and reduced female fecundity due to abnormal meiosis following cre recombination. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
