Primary Identifier | MGI:106654 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 17954 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity; histone acetyltransferase regulator activity; and histone binding activity. Acts upstream of or within positive regulation of neuron differentiation and regulation of stem cell division. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in nervous system. Orthologous to human NAP1L2 (nucleosome assembly protein 1 like 2). PHENOTYPE: Chimeric embryos with high contribution from heterozygous or homozygous null mutant ES cells exhibit severely abnormal neural tube development and die by embryonic day 14 (E14). [provided by MGI curators] |