| Primary Identifier | MGI:88362 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 12592 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including blood vessel development; labyrinthine layer development; and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; extraembryonic component; genitourinary system; gut; and neural tube. Orthologous to human CDX4 (caudal type homeobox 4). PHENOTYPE: Male mice hemizygous or female mice homozygous for a reporter/null allele exhibit defects in embryonic erythropoiesis. Male mice hemizygous for a knock-out allele display a subtle anterior transformation at the level of vertebra 15 with extremely low penetrance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
