|  Help  |  About  |  Contact Us

ncRNA Gene : Xist inactive X specific transcripts

Primary Identifier  MGI:98974 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  213742
Mgi Type  lncRNA gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ribonucleoprotein complex binding activity. Acts upstream of or within inactivation of paternal X chromosome by genomic imprinting; random inactivation of X chromosome; and spongiotrophoblast differentiation. Located in X chromosome and nuclear body. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; neural retina; and spleen. Orthologous to human XIST (X inactive specific transcript).
PHENOTYPE: Xist function in X-inactivation is disrupted in females carrying a null mutation. Depending on maternal or paternal derivation of the mutation, females survive or die in early embryogenesis. In either case, X-inactivation is non-random and abnormal. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI314753,
  • Xist,
  • MGI:2147863,
  • inactive X specific transcripts,
  • MGD-MRK-15474,
  • AI314753

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Targeted By

0 Targets

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For