| Primary Identifier | MGI:2148316 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 272790 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including brain; dorsal root ganglion; egg cylinder; liver; and reproductive system. Orthologous to human MAGEE2 (MAGE family member E2). PHENOTYPE: Male mice hemizygous for a knock-out allele exhibit enlarged brain structures with a marked increase in total granular retrosplenial cortex area and in total brain area. In contrast, homozygous females show an opposite but non-significant trend towards reduced brain size. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
