| Primary Identifier | MGI:3045213 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 279572 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and rRNA binding activity. Involved in innate immune response and toll-like receptor 13 signaling pathway. Acts upstream of or within MyD88-dependent toll-like receptor signaling pathway; regulation of MAPK cascade; and response to virus. Located in endosome. Is expressed in vibrissa. PHENOTYPE: Macrophages isolated from mice carrying an ENU-induced mutation respond normally to known TLR ligands and can contain various viral infections; however, mice carrying this allele have not been tested for immune responses in vivo. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
