Primary Identifier | MGI:1925384 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 78134 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lysophosphatidic acid binding activity and lysophosphatidic acid receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in plasma membrane. Is expressed in several structures, including branchial arch; cardiovascular system; future brain; limb; and sensory organ. Orthologous to human LPAR4 (lysophosphatidic acid receptor 4). PHENOTYPE: A subset of mice homozygous for a null allele fail to survive gestation and exhibit hemorrhages and/or edema in many organs at multiple embryonic stages, as well as dilated blood and lymphatic vessels, and impaired recruitment of smooth muscle cells and pericytes. [provided by MGI curators] |