| Primary Identifier | MGI:1914657 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 67407 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein homodimerization activity. Acts upstream of or within several processes, including acrosome assembly; maintenance of cell number; and single fertilization. Is active in acrosomal membrane and perinuclear theca. Used to study male infertility. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 8. Orthologous to human CYLC1 (cylicin 1). PHENOTYPE: Mice homozygous for a null mutation reduced male fertility with detached acrosomes, fan-shaped sperm heads, and impaired fertilization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
