| Primary Identifier | MGI:2450016 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 237038 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables superoxide-generating NAD(P)H oxidase activity. Acts upstream of or within several processes, including cellular response to hyperoxia; oxygen metabolic process; and positive regulation of intracellular signal transduction. Located in endosome. Orthologous to human NOX1 (NADPH oxidase 1). PHENOTYPE: Male mice hemizygous for one mutation show abnormal blood vessel morphology and physiology with decreased basal systolic blood pressure. Male hemizygotes for two null mutations exhibit abnormal response to angiotensin II. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
