Primary Identifier | MGI:107432 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 13497 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable zinc ion binding activity. Predicted to be involved in synapse organization and synaptic signaling. Located in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and hemolymphoid system gland. Orthologous to human DRP2 (dystrophin related protein 2). PHENOTYPE: Mice homozygous for a conditional allele activated in peripheral nerves exhibit abnormal Scwann cell morphology, supernumerary Schwann cell, abnormal myelin sheath morphology and hypermyelination. [provided by MGI curators] |