Primary Identifier | MGI:1933192 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 83454 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA binding activity. Acts upstream of or within poly(A)+ mRNA export from nucleus. Located in nuclear envelope. Is expressed in central nervous system; sensory organ; and testis. Orthologous to several human genes including NXF2 (nuclear RNA export factor 2) and NXF2B (nuclear RNA export factor 2B). PHENOTYPE: Male mice heterogyzous for the null allele exhibit reduced fertility associated with abnormal meiosis or reduced spermatogonia proliferation depending on strain background. [provided by MGI curators] |