Primary Identifier | MGI:3614797 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 622473 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including Notch signaling pathway; bone morphogenesis; and somite rostral/caudal axis specification. Predicted to be active in nucleus. Is expressed in somite; tail unsegmented mesenchyme; tongue; and trunk unsegmented mesenchyme. Orthologous to human RIPPLY1 (ripply transcriptional repressor 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit extension of the seventh cervical vertebrae that fuses with the first rib. However, mice are otherwise viable. [provided by MGI curators] |