Primary Identifier | MGI:1933172 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 83453 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables BMP binding activity and transforming growth factor beta binding activity. Involved in several processes, including BMP signaling pathway; excitatory chemical synaptic transmission; and synapse organization. Is active in extracellular region. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; neural ectoderm; and skeletal system. Orthologous to human CHRDL1 (chordin like 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered kinetics of synaptic events, reduced glutamate receptors and increased plasticity in the visual cortex. [provided by MGI curators] |