Primary Identifier | MGI:1100850 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 12338 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity. Involved in microtubule bundle formation and regulation of cytoskeleton organization. Located in microtubule. Is expressed in several structures, including body cavity or lining; lung; metanephros; tongue; and trunk. Orthologous to human CAPN6 (calpain 6). PHENOTYPE: Female mice homozygous for a knock-out allele display advanced skeletal muscle development during embryogenesis and advanced skeletal muscle regeneration after cardiotoxin-induced degeneration. Male hemizygotes exhibit increased differentiation of primary cultured skeletal muscle cells. [provided by MGI curators] |