Primary Identifier | MGI:3588192 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 619287 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nucleic acid binding activity and zinc ion binding activity. Acts upstream of or within cognition and norepinephrine metabolic process. Is expressed in several structures, including brain; gonad; immune system; liver; and lung. Orthologous to human RTL4 (retrotransposon Gag like 4). PHENOTYPE: Homozygous null mice exhibit abnormal behavior including hyperactivity and abnormal responses to a new environment, and abnormal working memory and cognition. Neuronal norepinephrine levesl are slow to recover after induced neurotransmitter release. Mortality, growth, kidney function, and reproductive system biology are all unaffected. [provided by MGI curators] |