| Primary Identifier | MGI:108440 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 27494 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable angiostatin binding activity and signaling receptor activity. Acts upstream of or within several processes, including gastrulation; negative regulation of GTPase activity; and vasculogenesis. Located in bicellular tight junction; cytoplasmic vesicle; and lamellipodium. Is expressed in several structures, including egg cylinder; embryo endoderm; embryo mesoderm; and mesendoderm. Orthologous to human AMOT (angiomotin). PHENOTYPE: Homozygotes for a null mutation exhibit impaired migration into proximal extraembryonic regions resulting in furrows of visceral endoderm at the junction of embryonic and extraembryonic regions, vascular insufficiency in the intersomitic region, dilated vessels in the brain and embryonic lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
