Primary Identifier | MGI:1924872 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 77622 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' DNA exonuclease activity; and phosphoric diester hydrolase activity. Predicted to be involved in base-excision repair. Located in mitochondrial inner membrane and nucleus. Orthologous to human APEX2 (apurinic/apyrimidinic endodeoxyribonuclease 2). PHENOTYPE: Hemizygous null male mice display mild growth retardation, thymic atrophy, reduced white blood cell counts, and a slight decrease in red blood cell count. [provided by MGI curators] |