| Primary Identifier | MGI:2652875 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 279561 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable molecular condensate scaffold activity; potassium channel inhibitor activity; and protein serine/threonine kinase activity. Involved in negative regulation of pancreatic juice secretion. Acts upstream of or within cell volume homeostasis and maintenance of blood-brain barrier. Located in adherens junction and bicellular tight junction. Human ortholog(s) of this gene implicated in Prieto syndrome. Orthologous to human WNK3 (WNK lysine deficient protein kinase 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lower blood pressure when fed a low-salt diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
