| Primary Identifier | MGI:2442430 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 245671 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in aggresome; cytosol; and nucleoplasm. Is expressed in early conceptus; inner cell mass; and liver. Orthologous to human KLF8 (KLF transcription factor 8). PHENOTYPE: A subset of male chimeras hemizygous for a gene trapped allele exhibit embryonic growth retardation. Mice heterozygous and homozygous for a gene trap allele exhibit premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
