| Primary Identifier | MGI:1860283 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 54609 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; molecular condensate scaffold activity; and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including negative regulation of receptor-mediated endocytosis; proteolysis involved in protein catabolic process; and regulation of catabolic process. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 15. Orthologous to human UBQLN2 (ubiquilin 2). PHENOTYPE: High level overexpression of wild-type peptide leads to progressive retinal degradation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
