| Primary Identifier | MGI:98233 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 20229 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable diamine N-acetyltransferase activity; identical protein binding activity; and spermidine binding activity. Acts upstream of or within regulation of cell population proliferation. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human SAT1 (spermidine/spermine N1-acetyltransferase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility, increased percent body fat and total fat pad weight, abnormal liver and white adipose tissue physiology, abnormal aerobic energy metabolism, increased serum leptin levels, and increased weight gain on a high-fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
