Primary Identifier | MGI:1859815 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 53381 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Acts upstream of or within several processes, including cell redox homeostasis; negative regulation of male germ cell proliferation; and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Located in cytosol and endoplasmic reticulum. Is expressed in several structures, including nervous system. Orthologous to human PRDX4 (peroxiredoxin 4). PHENOTYPE: Mice homozygous for a null allele exhibit decreased testicular weight, testis atrophy, and oligozoospermia due to increased apoptosis associated with oxidative damage. [provided by MGI curators] |