Primary Identifier | MGI:1194910 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 245688 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of ESC/E(Z) complex and NuRD complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Orthologous to human RBBP7 (RB binding protein 7, chromatin remodeling factor). PHENOTYPE: Male chimeras hemizygous for a gene trapped allele exhibit posterior patterning and embryo turning defects. [provided by MGI curators] |