| Primary Identifier | MGI:2448558 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 237211 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including bone marrow development; cellular response to camptothecin; and regulation of double-strand break repair via homologous recombination. Predicted to be located in chromatin. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in cerebral cortex ventricular layer and cortical plate. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group B and head and neck squamous cell carcinoma. Orthologous to human FANCB (FA complementation group B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility with oligozoospermia, reduced primordial germ cells and defects in the maintenance of undifferentiated spermatogonia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
