Primary Identifier | MGI:1196332 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 11856 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activator activity. Involved in positive regulation of GTPase activity. Acts upstream of or within actin filament organization and focal adhesion assembly. Located in actin cytoskeleton. Is expressed in lower leg bone. Used to study microphthalmia. Orthologous to human ARHGAP6 (Rho GTPase activating protein 6). PHENOTYPE: Mice homozygous for a targeted null mutation do not exhibit any observable abnormalities. [provided by MGI curators] |