| Primary Identifier | MGI:2151017 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 192140 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables mechanosensitive monoatomic ion channel activity and voltage-gated calcium channel activity. Acts upstream of or within several processes, including detection of mechanical stimulus involved in sensory perception of sound; regulation of calcium ion transmembrane transport; and vestibular reflex. Located in cuticular plate and stereocilium tip. Is expressed in inner ear. Orthologous to human TMC2 (transmembrane channel like 2). PHENOTYPE: Mice homozygous for a null allele display normal hearing and motor behavior. Cochlear hair cells show partial resistance to gentamicin induced toxicity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
