| Primary Identifier | MGI:87968 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 269378 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables several functions, including NAD binding activity; adenosylhomocysteinase activity; and copper ion binding activity. Acts upstream of or within S-methylmethionine cycle. Located in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm and hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Orthologous to human AHCY (adenosylhomocysteinase). PHENOTYPE: Mice heterozygous for a null allele exhibit endothelium dysfunction and oxidative stress. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
