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Protein Coding Gene : P2ry1 purinergic receptor P2Y, G-protein coupled 1

Primary Identifier  MGI:105049 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  18441
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Predicted to enable several functions, including A1 adenosine receptor binding activity; G protein-coupled purinergic nucleotide receptor activity; and adenyl ribonucleotide binding activity. Acts upstream of or within positive regulation of monoatomic ion transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and liver and biliary system. Orthologous to human P2RY1 (purinergic receptor P2Y1).
PHENOTYPE: Mice homozygous for either one of two independently generated knock-out alleles exhibit decreased platelet aggregation, increased bleeding time, and resistance to induced thromboembolism. [provided by MGI curators]
  • synonyms:
  • P2y1r,
  • P2Y1,
  • P2Y1 receptor,
  • P2ry1,
  • purinergic receptor P2Y, G-protein coupled 1,
  • MGD-MRK-32088

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For