| Primary Identifier | MGI:105049 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 18441 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable several functions, including A1 adenosine receptor binding activity; G protein-coupled purinergic nucleotide receptor activity; and adenyl ribonucleotide binding activity. Acts upstream of or within positive regulation of monoatomic ion transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and liver and biliary system. Orthologous to human P2RY1 (purinergic receptor P2Y1). PHENOTYPE: Mice homozygous for either one of two independently generated knock-out alleles exhibit decreased platelet aggregation, increased bleeding time, and resistance to induced thromboembolism. [provided by MGI curators] |