| Primary Identifier | MGI:2682211 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 381489 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables hormone binding activity. Acts upstream of or within several processes, including lung connective tissue development; nipple morphogenesis; and parturition. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; aorta; genitourinary system; heart; and lung. Orthologous to human RXFP1 (relaxin family peptide receptor 1). PHENOTYPE: Mice homozygous for disruptions in this gene display reduced male fertility, particularly at younger ages and early generations. Impaired nipple development prevents nursing by females. [provided by MGI curators] |