| Primary Identifier | MGI:1333831 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 16429 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables oligosaccharide binding activity. Involved in response to nematode. Located in brush border membrane and membrane raft. Is expressed in several structures, including brain; eye; genitourinary system; gut; and immune system. Orthologous to several human genes including ITLN1 (intelectin 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit inflammatory bone loss-like phenotypes including increased proinflammatory cytokine levels, increased osteoclast formation and bone tissue destruction, decreased osteoblast proliferation and enhanced proliferation of osteoclast progenitors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
