| Primary Identifier | MGI:1924074 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 76824 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrion. Orthologous to human MTFR1L (mitochondrial fission regulator 1 like). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered Parkin abundance in the heart, impaired stress-induced cardiac mitophagy, increased mitochondrial damage, and accelerated age-related cardiac dysfunction, inflammation, and cellular senescence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
