| Primary Identifier | MGI:109538 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12854 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable G protein-coupled receptor binding activity and neuropeptide hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway; regulation of cell migration; and regulation of circadian sleep/wake cycle, sleep. Predicted to be active in extracellular region. Is expressed in central nervous system and retina. Orthologous to human CORT (cortistatin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased circulating growth hormone and adrenocorticotropin, decreased serum prolactin, and insulin resistance and increased serum glucose level in male mice. [provided by MGI curators] |