| Primary Identifier | MGI:2443755 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 320292 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in early endosome; late endosome; and midbody. Predicted to be active in plasma membrane. Is expressed in brain; branchial arch; limb bud; vestibulo-cochlear ganglion; and vibrissa. Orthologous to human RASGEF1B (RasGEF domain family member 1B). PHENOTYPE: Mice with loss of expression display reduced anxiety-like and increased compulsive behavior with abnormalities in microglia and TNF levels in parts of the brain. [provided by MGI curators] |