| Primary Identifier | MGI:88610 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 13113 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable several functions, including caffeine oxidase activity; retinoic acid 4-hydroxylase activity; and steroid hydroxylase activity. Acts upstream of or within positive regulation of gene expression and xenobiotic transport. Predicted to be located in cytoplasm. Is expressed in heart; liver; lung; metanephros; and spleen. Human ortholog(s) of this gene implicated in alcohol-associated liver disease; essential hypertension; familial Mediterranean fever; and leukemia (multiple). Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5). PHENOTYPE: Mice homozygous for a knock-out allele show no apparent alterations in hematology, plasma clinical chemistry or pathology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
