| Primary Identifier | MGI:1196224 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 264064 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in negative regulation of triglyceride metabolic process; positive regulation of transcription by RNA polymerase II; and protein ubiquitination. Part of mediator complex. Is expressed in tibialis anterior and tongue. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human CDK8 (cyclin dependent kinase 8). PHENOTYPE: Mice homozygous for a gene-trapped allele die prior to implantation exhibiting fragmented blastomeres and failure to undergo compaction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
