| Primary Identifier | MGI:2443963 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 320405 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Involved in synaptic vesicle priming. Acts upstream of or within cellular response to starvation; hematopoietic stem cell homeostasis; and positive regulation of exocytosis. Located in cytoplasmic vesicle; postsynaptic membrane; and presynaptic membrane. Is active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and presynapse. Is expressed in several structures, including brain; genitourinary system; sensory organ; skeleton; and spinal cord. Used to study autism spectrum disorder. Orthologous to human CADPS2 (calcium dependent secretion activator 2). PHENOTYPE: Mice homozygous for a null allele exhibit defects in cerebellum, Purkinje cell and interneuron morphology, paired-pulse facilitation, and behaviors including emotional behavior, vestibuoocular reflex, circadium and sleep patterns, social investigation and nurturing behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
