| Primary Identifier | MGI:2676316 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 238406 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase activity. Predicted to be involved in male gonad development and proteolysis. Located in external side of plasma membrane and sperm head plasma membrane. Part of protein-containing complex. Orthologous to human ADAM6 (ADAM metallopeptidase domain 6 (pseudogene)). PHENOTYPE: Mice homozygous for null alleles of Adam6a and Adam6b exhibit severely reduced male fertility associated with impaired sperm to sperm interactions and sperm binding to zona pellucida. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
