| Primary Identifier | MGI:107935 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 16206 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable signaling receptor activity. Acts upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; heart; integumental system; and sensory organ. Orthologous to human LRIG1 (leucine rich repeats and immunoglobulin like domains 1). PHENOTYPE: Homozygous null mice developed psoriasiform epidermal hyperplasia. Homozygotes exhibit hair follicle, epidermis, vertebral, eye and hearing abnormalities, decreased body size and fat amount, and increased susceptibility to bacterial infection. [provided by MGI curators] |