Primary Identifier | MGI:1923736 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 76486 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within binding activity of sperm to zona pellucida and flagellated sperm motility. Located in acrosomal vesicle; cell surface; and plasma membrane. Is expressed in several structures, including central nervous system; reproductive system; retina; spleen; and stomach. Orthologous to human LY6K (lymphocyte antigen 6 family member K). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with impaired sperm migration into the oviduct. [provided by MGI curators] |